经皮穿刺臭氧注射术治疗腰椎间盘突出症的临床研究

Clinical study of percutaneous injection of intradisc and intervertebral foramen with ozone to treat lumbar disc herniation

目的探讨经皮穿刺臭氧注射术对腰椎间盘突出症的疗效及安全性。方法64例患者经CT或MRI检查证实为腰椎间盘突出症,均表现为腰背痛及下肢麻痛,其中间盘膨出23例,突出41例。在C形臂X线透视监视下采用21G多侧孔酒精穿刺针经皮穿刺至腰椎间盘,实施盘内及椎间孔臭氧注射术。盘内注射10 ml,椎间孔注射15 ml,臭氧浓度为盘内50μg／ml,椎间孔40μg/ml。结果术后5 d总有效率为90．6％(58／64例),显效26例(40．6％),有效32例(50％),无效6例(9．38％),随访3～6个月,总有效率84．4％(54／64例),无任何严重并发症发生。结论经皮穿刺臭氧注射术是治疗腰椎间盘突出症的一种安全、有效的方法。

Objective To evaluate the therapeutic effect and safety of intradiscal and intervertebral foramen injection with ozone on lumbar disc herniation. Methods Sixty four patients with the symptoms of sciatica and low back pain were selected,including 23 cases with disc bulging,41 protrusion diagnosed by CT or MRI. A 21G needle was punctured into the disc and intervertebral foramen, 10 ml ozone at 50 μg/ml and 15 ml at 40 μg/ml were injected respectively. Results The patients were followed up from 3 to 6 months after treatment. The therapeutic effect showed that 26 patients （40.6%） had excellent recovery, and 32 cases （50%） had significant relief of symptoms, and 6 patients （9.38%） got failure. After 3 to 6 months follow-up, the rate of excellent and good were 84.4% （54/64 cases）, No serious complications occurred. Conclusion The method of ozone injection into lumbar intervertebral disc and foramen is a safe and effective method for the treatment of the lumbar disc herniation.