期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

微小RNA及其功能的研究进展 被引量：2

Advances of micro-RNAs and its functions
下载PDF
导出
摘要 microRNAs（miRNAs）是近来研究发现的一类长度在21-30 nt的调控RNA,其参与细胞生长、组织分化和肿瘤形成等各种过程。本文就microRNAs作用机制及其功能的研究进展作一综述。 MicroRNAs（miRNAs） are small non-coding RNA gene products about 21-30 nt long that receive close attention for their correlation with cell growth,tissue differentiation and oncogenesis. This paper reviews research advancement on microRNAs and its functions.
作者 李雷佳 许树长
机构地区 同济大学附属同济医院消化科
出处 《同济大学学报（医学版）》 CAS 2007年第2期105-108,共4页 Journal of Tongji University(Medical Science)
关键词 MICRORNAS 基因调控 肿瘤形成 作用机制 功能 MicroRNAs gene regulation oncogenesis
分类号 R394 [医药卫生—医学遗传学]
  • 相关文献

参考文献20

  • 1Zarnore PD, Haley B. The big world of small RNAs[J].Science,2005,309 : 1519 - 1524.
  • 2Chen CZ. MicroRNAs as oncogenes and tumor suppressors[J]. N Engl J Med,2005,353(17) : 1768 - 1771.
  • 3Reinhart BJ, Slak FJ, Basson M, et al. The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans[J]. Nature,2000,403(6772) .901 - 906.
  • 4Yekta S, Shih IH, Barrel DP, et al. MicroRNA-directed cleavage of HOXB8 mRNA[J ]. Science, 2004,304 : 594- 596.
  • 5Esquela AE, Slack FJ. Oncomirs-microRNAs with a role in cancer[J ]. Nature Reviews, 2006,6: 259 - 269.
  • 6Hipfner DR, Weigmann K, Cohen SM, et al. The bantam gene regulates Drosophila growth [ J ]. Genetics, 2002,161 : 1527 - 1537.
  • 7Chen Jian-fu, Mandel EM, Thomson JM, et al. The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation [ J ]. Nature genetics,2006,2( 1 ) :228 - 233.
  • 8Chang S, Johnston RJ, Frokjaer JC, et al. MicroRN As act sequentially and asymmetrically to control chemosensory laterality in the nematode [ J ]. Nature, 2004,430 :785 - 789.
  • 9Giraldez AJ, Cinalli RM, Glasner ME, et al. MicmRNAs regulate brain morphogenesis in zebrafish [ J ]. Science,2005,308:833 - 838.
  • 10Poy MN, Eliasson L, Krutzfeldt J, et al. A pancreatic islet specific microRNA regulates insulin secretion [J ].Nature, 2004,432 : 226 - 230.

同被引文献19

  • 1孙建国,廖荣霞,周度金,陈正堂.基于基因芯片的乳腺癌干细胞miRNAs检测分析[J].重庆医学,2007,36(13):1280-1282. 被引量：13
  • 2Garzon R, Calin GA, Croce CM. MicroRNAs in cancer[ J]. Annu Rev Med, 2009,60 : 167 - 179.
  • 3Friedman RC, Farh KK, Burge CB, et al. Most mammalian mRNAs are conserved targets of micro- RNAs[ J]. Genome Res, 2009,19( 1 ) : 92 - 105.
  • 4Bringmann A, Pannicke T, Grosche J, et al. Muller cells in the healthy and diseased retina [ J ]. Prog in Retinal and Eye Res, 2006,25(4) : 397-424.
  • 5Jadhav AP, Roesch K, Cepko CL. Development and neurogenic potential of Muller glial cells in the vertebrate retina [ J ]. Prog in Retinal and Eye Res, 2009,28 (4) : 249 - 262.
  • 6Das AV, Mallya KB, Zhao X, et al. Neural stem cell properties of Muller glia in the mammalian retina: regulation by Notch and Wnt signaling [ J ]. Dev Biol, 2006,299( 1 ) : 283 - 302.
  • 7Ryan D, Oliveira-Fernandes M, Lavker R. MicroRNAs of the mammalian eye display distinct and overlapping tissue specificity [ J~. Mol Vis, 2006,12 (134 -35) : 1175 - 1184.
  • 8Karali M, Peluso I, Gennarino VA, et al. miRNeye: a.microRNA expression atlas of the mouse eyeE J]. Bmc Genomics, 2010,11: 715.
  • 9Xue X, Sun J, Zhang Q, et al. Identification and characterization of novel microRNAs from Schistosoma japonicumE J]. Plos One, 2008,3 (12) : e4034.
  • 10Chen C, Ridzon DA, Broomer A J, et al. Real-time quantification of microRNAs by stem-loop RT-PCR I J ]. Nucleic Acids Res, 2005,33 (20) : e179.

引证文献2

二级引证文献6

同济大学学报（医学版）
2007年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部