红绒毛羊蹄甲中的二氢黄酮醇苷和黄烷醇类成分

Dihydroflavonol glycosides and flavan-3-ols from Bauhinia aurea

目的:研究红绒毛羊蹄甲Bauhinia aurea的化学成分。方法:应用各种色谱技术进行分离纯化,用MS和NMR分析确定化合物结构。结果:从红绒毛羊蹄甲90%乙醇提取物的醋酸乙酯萃取部位中分离得到8个化合物,分别鉴定为异黄杞苷(1)、落新妇苷(2)、新落新妇苷(3)、异落新妇苷(4)、新异落新妇苷(5)、(2R,3S)-儿茶精6)、(2R,3R)-表儿茶精(7)和(2R,3R)-3-O-没食子酰表儿茶精(8)。结论:除化合物2,6和8外,其余5个化合物均属首次从该属植物中发现。

Objective： To study the chemical constituents ofBauhinia aurea. Method： The compounds were isolated by column chromatography over silica gel, reversed-phase RP-18, and Sephadex LH -20. MS and NMR spectroscopic methods were used to determine structures of purified compounds. Result： Eight compounds were isolated from the ethyl acetate soluble fraction of the ethanolic extract and their structures were elucidated as isoengeletin （1）, astilbin （2）, neoastilbin （3）, isoastilbin （4）, neoisoastilbin （5）, （ ＋ ）-catechin （6）, （ - ）-epicatechin （7） and （ - ）-epicatechin 3-O-gallate （8）. Conclusion： Five compounds were isolated from this genus for the first time except for 2, 6 and 8.