香港远志化学成分的分离与鉴定Ⅱ

Isolation and structure identification of chemical constituents from Polygala hongkongensis Ⅱ

目的：分离和鉴定香港远志全草的化学成分。方法：应用硅胶,Sephadex LH-20及半制备HPLC等柱色谱法进行分离、纯化,根据NMR和MS光谱数据确定化合物结构。结果：得到6个化合物,分别为1,7-二羟基酮（1）,1,3,6-三羟基酮（2）,1,4,7-三羟基-3-甲氧基酮（3）,对羟基苯甲酸（4）,3,4-二羟基苯甲酸（5）,2,5-二羟基苯甲酸甲酯（6）。结论：化合物1-6均为首次从该植物中得到。

Objective： To isolate and elucidate the constituents of herbs of Polygala hongkongensis. Method： The constituents were isolated and purify by chromatographic on silica gel, Sephadax LH-20 and semi-preparative HPLC. The structures were determined by NMR and MS spectral analysis. Result： Six compounds were identified as euxanthone （1）, 1, 3, 6-trihydroxyxanthone （2）, 1,4, 7-trihydroxy-3-methoxy-xanthone （3）, p-hydroxybenzoic acid （4）, 3, 4-dihydroxybenzoic acid （5）, and methy 1 2, 5- dihydroxybenzoate （6）. Conclusion： The known compounds 1-6 were isolated from this plant for the first time.