狗股动脉准分子激光加球囊血管成形术即期效果观察

Experimental Study of the Early Efficacy of Excimer Laser Operation Plus Adjunctive Balloon Angioplasty on Dog′s Femoral Artery

对２０条血栓闭塞性狗股动脉行准分子激光血管成形术（ＥＬＡ），血管再通率为８５％（１７／２０），并发症为血管穿孔，发生率为１５％（３／２０），所有再通血管均加用球囊血管扩张成形术（ＢＡ），血管直径及残余狭窄程度均进一步改善（ＢＡ：２．０４±０．１６ｍｍＶｓＥＬＡ：１．２０±０．１４ｍｍ，Ｐ＜０．０５，ＢＡ：２０±７％ＶｓＥＬＡ：５４±５％，Ｐ＜０．０１），表明准分子激光加球囊扩张血管成形术是治疗外周闭塞性血管疾病的安全有效方法之一。

The effect of a domestically manufactured excimer laser performed operation together with adujunctive balloon angioplasty in achieving revascularization and reduction of residual stenosis was assessed. 20 femoral arteries with thrombosis and occlusion from 10 dogs were subjected to angiography. At first an excimer laser angioplasty was done followed by the balloon angioplasty. The diameters and residual stenosis of revascularized vessels were measured. The result showed that 17 out of 20 vessels (85%) were revascularized. The typical diameter of the revascularized vessels after excimer laser treatment was 1.20±0.14 mm, while residual stenoses were54%±5%. After an adjunctive balloon angioplasty the diameter and residual stenoses were 2.04±0.16 mm and 20%±7% respectively (P<0.05 and P<0.01). Complication in a form of vasoperforation occurred in 3/20 vessels (15%). It is concluded that China manufactured excimer laser angioplasty is effective when used for revascularization. The reduction of narrowing and residual stenoses was enhanced after adjunction of the balloon angioplasty. It would be expected that this method can be employed in treating peripheral occlusive disease effectively and safely.