急性心肌梗死病人血浆中D-二聚体、可溶性细胞间粘附分子的检测与分析

Study of blood plasma D-dimer and soluble inter-cellular adhesion molecule-1 in patiens with acute miocardial infarction

目的:通过检测心肌梗死病人(AMI)血浆中D-二聚体(DD)和可溶性细胞间粘附分子(SICAM-1)的含量,探讨其二者与AMI的相关性。方法:分别测定45例AMI患者和41例健康对照者血浆中的DD和SICAM-1含量,将患者组与对照组进行比较。结果:AMI组DD和SICAM-1含量明显高于对照组,差异均有显著性,DD与正常组比较,P<0.01,SICAM-1与正常组比较,P<0.05。结论:SIAM-1和DD参与了AMI的病理过程。

Objective： To detect the concentration of D - dimer and soluble inter - cellular adhesion molecule - 1 in blood plasma in patients with acute myocardial infarction. Methods：D - dime （DD） and soluble inter - cellular adhesion molecule - 1 （ SICAM - 1 ） in blood plasma of 45 patients with acute myocardial infarction （AMI） and 41 normal controls were measured by ELISA. Results： Compared with AMI and control group, the level of DD and SICAM - lwere significantly higher in patients with AMI than in control. DD （P 〈0.01 ）, SICAM- 1 （P 〈0.05 ）. Conclusions： DD and SICAM -1 participate in the AMI on that happen and development.