超声评价冠心病、糖尿病及高血压病与颅外颈动脉斑块形成的关系

Evaluation on the relationship between cerebral vascular disease and the form of carotid atherosclerotic plaque

目的:探讨心脑血管疾病与颈动脉粥样硬化斑块形成的相互关系。方法:选择186例三种疾病(高血压病60例、冠心病67例、糖尿病59例)的患者,用Logiq400彩色多普勒动态检测颈总动脉(CCA)、颈内动脉(ECA)、颈外动脉(ICA)的内膜-中膜厚度变化参数和颈动脉斑块分布位置。结果:发现186例的颈动脉粥样硬化斑块,多见于颈动脉的分叉部(球部)和ICA起始段2.0 cm范围内,易见颈动脉粥样硬化斑块形成(80%分布在此处),斑块直径约2 cm^2.2 cm,颈动脉内膜-中膜厚度与健康组相比差异有显著性(P<0.05~0.001)。结论:临床表明颈动脉粥样硬化斑块和颈动脉内膜-中膜的增厚,是心、脑血管疾病的危险因素,它们的形成影响了心脑血管的结构和功能。通过超声彩色多普勒动态观察可以尽早发现动脉粥样硬化的形成,并检测出小的狭窄性动脉粥样硬化斑的位置,从而能为患者提供有效的干预措施和治疗方案。

Objective：To investigate the relationship between cerebral vascular disease and the form of carotid atherosclerotic plaque. Methods： 186 patients with three kinds of diseases （ hypertension 60 ,coronary heart disease 67 ,diabetes 59 ） were measured by LOGIQ 400 transcutaneous ultrasound of the parameter changes of internal - central membrane thickness including CCA （ Central Carotid Artery） , ICA （ Interior Carotid Artery） ,ECA （ Exterior Carotid Artery ） and the distributing place of carotid atherosclerotic plaque. Resuits： In the three kinds of disease, carotid atherosclerotic plaque had different distribution and the carotid artery internal - central membrane thickness show such a difference between 186 patients and healthy persons matched values （P 〈 0.05 -0.001 ）. The diameter of atherosclerotic plaque was about （2 -2.2 cm）, they appeared on the branch of carotid which narrow area were about 80%. Conclusions： The results indicate that the form of carotid atherosclerotic plaque was discovered as early as possible by ecbocardiography and then we can constitute RX in effect for patient.