PSA降低不育患者精浆粘度的实验室观察

Reseach on how to depress semenial viscosity of infertile men by PSA

目的:探索用前列腺特导性抗原(PSA)治疗男性不育患者精液的效果。方法:将精液标本按精液粘度分为:粘度正常组30例,高粘度组32例,分别检测PSA含量,并向高粘度组精液加入PSA,观察精液变化。结果:PSA含量比较:精液粘度正常组为(1.34±0.63)mg/ml,高粘度组为(0.69±0.31)mg/ml,两组比较差异有统计学意义(P<0.01),加入PSA使32例高粘稠度精液精子活动力和活动率改变有统计学意义。结论:PSA能降低高粘度精液的粘度,增强精子活力。

Objective：To explore the therapeutic effect of the seminal plasma in the male infertility using PSA. Methods：According to the semen viscosity, patients were divided into two groups： abnormal sperm viscosity group（n = 32） and normal sperm viscosity group（n =30） , The quantity of PSA in the sperm plasma was examined. The abnormal sperrm motility group was treated with PSA. Results： The PSA concentration was（ 1.34 ± 0.63 ） mg/ml in normal sperm viscosity group, （0.69 ± 0.31 ） mg/ml in abnormal sperm viscosity group;there were significant difference （P 〈 0.01 ）. Conclusions： PSA may depress the sperm viscosity and increase the sperm motility.