摘要
海藻酸钠是从海带或海藻中提取的天然多糖类化合物,作为缓释制剂辅料广泛应用于片剂、微丸、微囊、脂质体、纳米粒等缓释制剂中,现综述近年来海藻酸钠作为辅料的影响因素及在缓释制剂中的应用研究进展。
Alginate is a natural polysaccharide polymer isolated from seaweeds or algae, which is widely used as a sustained-release excipient of tablets, pellets, microspheres, liposome and nanoparti- cles. This paper reviews key elements that make sodium alginate used as excipients as well as recent pro- gresses of sodium alginate used in sustained-release formulation.
出处
《中国新药杂志》
CAS
CSCD
北大核心
2007年第8期591-594,共4页
Chinese Journal of New Drugs
关键词
海藻酸钠
缓释制剂
辅料
alginate sodium
sustained-release formulation
excipient
