中药多途径治疗慢性溃疡性结肠炎临床观察

The Clinical Observation on the Effection of Chinese Herbs via Multi-Route Treating Chronic Ulcerative Colitis

目的观察中药多途径治疗溃疡性结肠炎的临床疗效。方法将120例溃疡性结肠炎活动期患者随机分为两组,治疗组64例采用愈肠汤内服,同时予以石黄汤灌肠和外塞芙蓉叶栓剂;对照组56例予柳氮磺胺吡啶口服加灌肠。两组治疗20d后取标本测定过氧化氢酶(MDA)、超氧化物歧化酶(SOD)的含量。结果对照组肠黏膜中MDA水平与治疗组相比明显升高,而肠黏膜中SOD含量较治疗组显著下降。结论内服愈肠汤合石黄汤灌肠加外塞芙蓉叶栓剂治疗溃疡性结肠炎有较好临床疗效。

Objective： To observe the effection on ulcerative colitis（UC）. Methods： 120 patients were divided into the treatment group and the control group. Those in the treatment group（64 cases） were given Yuchang Decoction（愈肠汤） orally meanwhile Shihuang Decoction（石黄汤） an enema, combined with cottonrose hibiscus leaf epistom blocking anus. Those in the control group（56 cases） were given SASP orally and an enema. Patients in both groups were taken the specimen to measure the content of SOD and MDA 20 days later. Results： The content of MDA in the control group was obviously higher than in the treatment group, but the content of SOD in the control group is obviously lower than in the treatment group. Conclusion： The treatment, giving Yuchang Decoction orally and Shihuang Decoction an enema, combined with cottonrose hibiscus leaf episton blocking anus is effect for UC.