白藜芦醇类似物的合成研究

Synthesis of resveratrol analogues

以对硝基甲苯、3,4-二甲氧基苯甲醛为起始原料,经过缩合、还原、重氮化、亲核取代反应和酰化反应,最终合成新的5种目标化合物。用元素分析、红外光谱1、HNMR1、3CNMR及多种二维核磁共振谱确定了目标化合物的结构。

Five new compounds were synthesized from 3, 4- dimethoxybenzaldehyde and p-nitrotoluene via multiple steps, including condensation, catalytic reduction, diazotization, hydroxylation, nucleophilic substitution and acylation. The structures of these compounds have been determined by elemental analysis, IR spectra, ^1HNMR, ^13CNMR and two-dimensional NMR spectroscopy.