急性脑梗死患者血清甲状腺激素水平的测定及其临床意义

Detection of serum thyroid hormone level in patients with acute cerebral infarction and its clinical significance

目的:观察急性脑梗死患者血清甲状腺激素水平的变化,并探讨其临床意义。方法:采用化学发光法检测30例急性脑梗死者和30名健康对照者血清三碘甲状腺原氨酸(T3)、甲状腺素(T4)、促甲状腺素(TSH)水平,并对两组进行比较。结果:急性脑梗死患者血清T3、T4、TSH均低于对照者(P<0.01～P<0.001)。结论:急性脑梗死患者的甲状腺激素水平的改变可能是机体的保护反应,其对疗效观察、估计预后具有一定的指导价值。

Objective：To investigate the change of serum thyroid hormone in patients with acute cerebral infarction（ACI） and to explore its clinical significance. Methods： Serum triiodothyronine （ T3 ）, thyroxine （ T4 ） and thyroid-stimulating hormone （ TSH ） were detected by chemoluminescence assay in 30 cases of ACI and 30 normal controls,and the results were compared. Results：The levels of serum T3 , T4 and TSH were significantly lower in patients with ACI than in those of normal controls （ P 〈 0. 01 to P 〈 0. 001 ）. Conclusious ：The change of serum thyroid hormone in patients with ACI may be a protective reaction in human body,thus treatment that aims to this change is unnecessary.