肥大细胞在重症急性胰腺炎发病机制中的作用

Role of mast cells in the development of severe acute pancreatitis

重症急性胰腺炎是外科是常见的急腹症，迄今尚无特异性治疗。肥大细胞是重要炎症效应细胞，在重症急性胰腺炎发病机制中发挥重要作用，引起胰腺、肺、肠道等器官损害。肥大细胞稳定剂通过抑制其炎症反应，对重症急性胰腺炎时上述器官有重要的保护作用。

Severe acute pancreatitis is a kind of common acute abdomen in general surgery, and sofar we have not find an effective way to cure it. Mast cells is a kind of important inflammatory effector cells, in the process of severe acute pancreatitis causing damage of many organs such as pancreas, lung, intestine et al. Mast cell stabilizer can prevent the inflammatory process of severe acute pancreatitis, and protect these organs in the period of severe acute pancreatitis.