摘要
肝癌缺失基因（DLC-1）是一种肿瘤抑制基因，位于人类染色体8p21．3-22，在人类多种肿瘤中呈低表达或缺失，因其与肝癌发生，转移乃至复发关系密切，使其在早期发现肝癌，早期预测肝癌的转移复发及预后方面扮演重要角色。
Deleted in liver cancer-1 （DLC-1） gene is a tumor suppressor gene and locates at human chromosome 8p21.3 -22. It＇s low or absent expression has been found in a variety of human tumors. Because of the close correlation between the expression of DLC-1 and the growth, metastasis, and recurrence of the hepatocellnlar carcinoma, DLC-1 gene may play an important role in the early discovery and prediction,recurrence and prognosis of hepatocellular carcinoma.
出处
《国际外科学杂志》
2007年第5期333-335,共3页
International Journal of Surgery
关键词
肝癌缺失基因-1
肝癌
肿瘤抑制基因
deleted in liver cancer-1
hepatocellular carcinoma
tumor suppressor gene
