微波辐射下苄醇直接脱水合成苄醚

Synthesis of Benzyl Oxide by Direct Dehydration of Benzyl Alcohol Under Microwave Radiation

在微波辐射下,以对二甲苯为带水剂、碘化钾为催化剂,由苄醇直接脱水合成苄醚。通过测定折光率、红外光谱和元素分析,对产物结构进行了分析和鉴定;考察了催化剂用量、对二甲苯用量、微波辐射功率、微波辐射时间对苄醚收率的影响;进行了微波辐射法合成苄醚的重现性及与其他方法的比较研究。实验结果表明,微波辐射对碘化钾催化苄醇直接脱水合成苄醚具有显著的促进作用,在苄醇6.48g、碘化钾催化剂0.045g、带水剂对二甲苯3mL、微波辐射功率500W、微波辐射时间10min的优化条件下,苄醚的收率可达96.3%以上。该方法具有反应时间短、产物收率高、操作简便等特点。

Benzyl oxide was synthesized by dehydration of benzyl alcohol under microwave radiation with p - xylene as water entrainer and potassium iodide as catalyst. Products were identified by means of refractometry, IR and element analysis. Reproducibility experiments and comparison between method mentioned above and other method were carried out. Effects of catalyst dosage, water entrainer dosage, microwave power and radiation time on the synthesis were studied. Under optimal reaction conditions： benzyl alcohol 6.48 g, potassium iodide 0.045 g, water entrainer 3 mL, microwave power 500 W and radiation time 10 min, yield of benzyl oxide can reach 96.3 %. This method exhibits advantages of short reaction time, high yield and simple operation.