先天性肿瘤出生前诊断和出生后处理

Prenatal diagnosis and postnatal treatment of congenital tumor

目的讨论产前超声诊断胎儿肿瘤以及出生后治疗原则。方法回顾分析22例产前超声发现的先天性肿瘤的诊断和治疗。结果产前诊断时间为孕28周至孕35周,出生前发现的先天性肿瘤包括颈部淋巴管瘤1例,骶尾部畸胎瘤5例,腹膜后畸胎瘤和寄生胎各1例,肝脏血管内皮细胞瘤3例,肾上腺和腹膜后神经母细胞瘤6例,卵巢囊肿5例出生后22例均进行了超声检查和CT或核磁共振检查(MRI),影像学的主要发现与产前超声发现基本一致。22例中18例接受了手术治疗,4例卵巢囊肿自然消退。结论先天性肿瘤的出生前诊断给出生后早期治疗提供了保证,不同肿瘤的处理原则不同。

Objective To report and discuss the prenatal diagnosis and postnatal treatment of congenital neoplasm. Methods The prenatally diagnosed 22 cases of fetal tumor were retrospectively analyzed on the diagnosis and treatment. Results The 22 cases were prenatally diagnosed during the 28th and 35th week of gestation, including 1 case of cervical lymphangioma, 5 sacrococcygeal teratoma, 1 retroperitoneal teratoma, 1 fetus-in-fetu, 3 liver hemangioendothelioma, 6 adreanal and retroperitoneal neuroblastoma, and 5 ovarian cyst. All cases were examined by both ultrasonography, and CT or magnetic resonance imaging （MRI） after delivery. The main findings in postpartum imaging examination were similar to that of prenatal examination. 18 cases received surgical operation, and 4 cases of ovarian cyst underwent spontaneous regression. Conclusion The prenatal diagnosis of congenital tumor gives more opportunity for early postnatal treatment. The principles of intervention vary on different tumors.