苯二氮卓类药物依赖失眠症患者睡眠质量应付方式及人格特征的研究

Comparison study of the personality factor and coping styles and sleep quality in benzodiazepine drug dependence with insomnia

目的 探讨失眠症患者苯二氮卓类（BZD）药物依赖的人格特征和应付方式。方法 采用多导睡眠图、明尼苏达多相人格问卷（MMPI）、应付方式问卷对符合CCMD-3诊断标准的20例失眠症药物依赖组和20例非药物依赖组进行测评,并与20名正常人比较。结果 （1）失眠症组睡眠效率则明显低于对照组[（66.5±7.34）min,（86.45±6.58）min,P〈0.01],药物依赖组REM睡眠时间明显低于非依赖组[（27.40±7.67）min,（44.30±12.91）min,P〈0.05]。（2）失眠症组MMPI量表评定,2组在Hs、D、Hy、Pd、Pa、Pt的T分显著高于正常对照组（P〈0.01）,但2组比较差异无显著性（P（0.05）。（3）应付方式中失眠症组不成熟应付方式高于对照组、成熟应付方式低于对照组低于（P〈0.01）。依赖组和非依赖组比较,解决问题[（0.51±0.13）分,（0.63±0.14）分]、求助低于非依赖组,自责、幻想、退避评分高于非依赖组（P（0.05～0.01）。结论 失眠与患者人格特征关系密切,不成熟的应付方式与BZD药物依赖的形成有关。

Objective To explore the personality faetor and coping styles and sleep quality in BZC drug dependence insomnia. Methods Twenty BZD dependence with patients and Twenty non-dependence with patients met the criteria of CCMD-3 on insomnia and twenty normal eontrols were evaluated with the polysomnographic （PSG） ,Coping styles Questionnaire （CSQ） and Minnesota Muluphasic Personality Inventory （MMPI） . Results （1）There were signifieant differences of sleep efficiency between the patients with insomnia and normal control（66. 5 ± 7.34,86.45 ±6.58, P 〈 0.01 ） , and REM sleep of dependence group that than lower non-dependence group （ 27.40 ± 7.67,44.30 ± 12.91, P〈 0.05 ）. （2）The score of MMPI of insomnia patients were higher than that of the controls in Hs, D, Hy, Pd, Pa and Pt （ P 〈 0.01 ）, There were no significant differences between dependence and non-dependence groups in MMPI（ P 〈 0.05）. （3）There was a significant difference on maturate and immature coping style in patients with insonmia and normal control （ P 〈 0.01 ）. The scores of solving problem （0.51 ±0.13, 0.63 ±0.14） and seeking for help subscales in coping style ,＊ere lower in the dependence group; The scores of self-accusation fantasy and winee of dependence patient was higher than that of non-dependence patient with insomnia （ P 〈 0.05 -0.01 ）. Conclusion Insomnia has a close relationship with personality patterns, and immature coping style has influence on the development of BZD drag dependence with insomnia.