摘要
目的:探讨妊娠晚期妇女凝血及纤溶系统的改变与临床意义。方法:选取180例妊娠晚期(平均孕周37.5周)妇女,检测其血浆中凝血酶原时间(PT),活化全血凝固时间(APTT),纤维蛋白(FIB),D-二聚体(D-Dimer)等4项指标。选取健康非妊娠妇女45例作为对照。结果:妊娠晚期妇女血浆PT,APTT,FIB,D-Dimer值与对照组比较差异均有统计学意义(P<0.05)。结论:妊娠晚期妇女血液处于高凝状态,检测上述4项指标,对防止妊娠晚期血栓形成、妊娠高血压综合征等并发症有一定临床意义。
Objective: To evaluate changes in coagulation and fibrinolytic system in terminal pregnant women and their clinical significance. Methods: The concentrations of PT, APTT, FIB, and D-Dimer in 180 terminal pregnant women and 45 nonpregnant women were determined. Results:PT and APTT shortened in terminal pregnant women, with significant difference between terminal pregnant women and nonpregnant women( P 〈 0.05 ). The values of FIB and D-Dimer were higher in pregnant women, with significant difference between nonpregnant women and terminal pregnant women ( P 〈 0.05 ) . Conclusion: Pregnant women are in hypereoagulable state. The coagulation and fibfinolytic system can be applied to monitor thrombosis in pregnant women.
出处
《军事医学科学院院刊》
CSCD
北大核心
2007年第2期155-156,共2页
Bulletin of the Academy of Military Medical Sciences
关键词
妊娠晚期
凝血及纤溶系统
血栓形成
妊娠并发症
terminal pregnancy
coagulation and fibfinolytic system
thrombosis
pregnancy complications