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Neuroserpin在神经系统疾病中的实验研究进展

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摘要 Neuroserpin(NSP)是一种轴突选择性的神经丝氨酸蛋白酶抑制剂。在成人中枢神经系统内,它主要存在于新大脑皮质、海马结构、嗅球和杏仁核,而在大多数丘脑核、尾状核、壳核和小脑细胞中相对缺乏。在大脑内,NSP形成了十二烷基磺酸钠(SDS)这种稳定的复合物,抑制了组织型纤溶酶原激活剂(tPA)、尿激酶和纤维蛋白溶酶的活性。
出处 《中华神经科杂志》 CAS CSCD 北大核心 2007年第4期281-283,共3页 Chinese Journal of Neurology
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