摘要
We report a case of multiple duodenal, pancreatic, and gastric carcinoids. A 67-year old woman was admitted to our hospital for treatment of a duodenal carcinoid. Laboratory tests revealed that the patient was associated with macrocytic anemia and hypergastrinemia, and type A gastritis was shown by gastrofiberscopy. During surgery, another tumor was incidentally found in the head of the pancreas. The tumors in the duodenum and pancreas were completely excised by pancreatoduodenectomy and immunohistologically diagnosed as gastrin-and serotonin-producing carcinoids, respectively. Pathological examination revealed that in addition to the grossly found carcinoids, there were subclinical carcinoids, one of which was an endocrine cell micronest, located in the stomach and duodenum. The tumors in the duodenum, pancreas, and stomach showed different characteristics from one another morphologically and immunochemically. Although no definitive evidence has been obtained, some sort of genetic anomaly may have been involved in this case, and hypergastrinemia due to duodenal gastrinoma may induce multiple gastric carcinoids.
我们报导多重十二指肠、胰腺、胃的良性肿瘤的一个案例。A 67- 岁女人为十二指肠的良性肿瘤的治疗进入我们的医院。实验室测试表明病人与 macrocytic 和 hypergastrinemia 被联系，并且类型 A 胃炎被 gastrofiberscopy 显示出。在外科期间，另一个肿瘤顺便说一下在胰的头被发现。在十二指肠和胰的肿瘤被胰头十二指肠切除术完全切除并且 immunohistologically 作为促胃液素诊断了 -- 并且生产血清素的良性肿瘤分别地。病理学的检查表明除了非常发现的良性肿瘤，有无临床症状的良性肿瘤，其一是内分泌的房间 micronest，在胃和十二指肠定位了。在十二指肠，胰，和胃的肿瘤词法上从对方显示出不同特征并且免疫化学上。尽管没有权威的证据被获得了，某种基因异例可能涉及了这种情况，并且 hypergastrinemia 可以由于十二指肠的 gastrinoma 导致多重胃的良性肿瘤。
