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阿霉素对心肌影响的实验研究 被引量:2

Effect of Adriamycin-induced Cardiomyopathy in Rats
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摘要 阿霉素(adriamycin,ADM)临床上广泛用于多种恶性肿瘤的治疗,但ADM可致严重的心肌毒性。目前许多肿瘤疾病采取先化疗后麻醉、手术治疗方案,化疗药对心肌的损伤并没有引起临床医生的足够重视,尤其是麻醉科医生,我们应慎重考虑阿霉素等化疗药对心肌的影响,保障围手术期的安全。 Adriamycin is generally used in malignant tumor, but ADM induce severe cardiomyopathy. Nowdays many tumors are treated with chemotherapy first, then treated by surgery under anesthesia. Clinician don't reconstruction the adriamycininduced cardiomyopathy, especially anesthesiologist. We should consider severely the chemotherapy induced cardiomyopathy,and ensure the safety of the anaesthesia and operation.
出处 《医学与哲学(B)》 2007年第4期68-70,共3页 Medicine & Philosophy(B)
基金 广西壮族自治区科技厅青年基金资助项目‚项目编号:桂科青0135003
关键词 大鼠 化疗 麻醉 阿霉素 rat, chemotherapy, anaesthesia, adriamycin
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  • 1黄宇戈,谭建新.细胞因子与心肌损伤及腺苷对损伤的保护作用[J].广东医学院学报,2004,22(6):596-598. 被引量:3
  • 2赖永洪,翟莺莺,叶铁真.槲皮素对柔红霉素所致心肌损伤的保护作用[J].现代临床医学生物工程学杂志,2005,11(1):15-18. 被引量:7
  • 3王光武,赵轶卓,王凡,李才.亚硝酸盐对培养心肌细胞的直接作用[J].中国地方病学杂志,1995,14(6):345-347. 被引量:2
  • 4向道康,孙宗全,夏家红,董念国,杜心灵,张凯伦.左-卡尼汀心脏停搏液对心脏瓣膜置换术患者心肌细胞凋亡的影响[J].中华麻醉学杂志,2005,25(9):649-652. 被引量:7
  • 5Chandran K, Aggarwal D, Migrino RQ, et al. Doxorubicin inactivates myocardial cytochrome coxidase in rats: cardioprotection by Mito-Q[ J]. Biophys,2009,96(4) :1388-1398.
  • 6Rabelo E,De Angelis K, Boek P,et al. Bar oreflex sensitivity and oxidat-ive stress in adriamycin-induced heart failure [ J ]. Hypertension,2001,38(2) :576-578.
  • 7Anand S, Singh S, Nahar Saikia U, et al. Cardiac abnormalities in acute organophosphate poisoning [ J ]. Clin Toxicol, 2009,47 ( 3 ) : 230-235.
  • 8Swain SM, Whaley FS, Ewer MS. Congestive heart failure in patient streated with doxorubicin: a retrospective analysis of three trials [ J]. Cancer,2003,97( 11 ) :2869-2879.
  • 9Hazari MS,Haykal-Coates N, Winsett DW, et al. Continuous electrocardiogram reveals differences in the short-term cardiotoxic response of Wistar-Kyoto and. spontaneously hypertensive rats to doxurubicin[ J]. Toxicol Sci ,2009,110( 1 ) :224-234.
  • 10Hiraumi Y, lwai-Kanai E ,Baba S, et al. Granulocyte colony-stimulating factor protects cardiac mitochondria in the early phase of cardiac injury [ J ]. Am Physiol Heart Circ Physiol, 2009,296 ( 3 ) : 823 -832.

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