HBV DNA与HBVM的检测及临床应用评价

Inspecting 5974 cases of HA and HB with marked serum and its clinical sidgnificance

HBVDNA是乙型肝炎（乙肝）病毒复制最直接的指标，为探讨其在临床应用上的价值，通过5974例甲、乙型肝炎血清标志检测结果分析，对HBeAg阳性的含义有进一步的认识。发现它与HBeAg相关密切，在判断乙肝病毒复制时不能单凭HBeAg阳性，而应结合HBVDNA是否阳性；在判断乙肝病毒停止复制的康复期时也不能单凭HBeAg阴转、抗-HBe阳转，还应结合HBVDNA是否也阴转；同时还发现HBSAg阳性的合并甲型肝炎（甲肝）的感染率低（2．95％），而HBsAg阴性的合并甲肝的感染率高（15．36％）。

Abetract:HBV DNA is one of the most direct index indicating HBV is reproducting. We studied the result of in-specting five thousand and nine hundred seventy four case of hepatitis Aand B scrum markers and found that determiningthe HBV is reproducting you cannot only depend on HBeAg negaive while you have to consult if HBVDNA is detected aspositive :determining HBV stop reproducting. you cannot only depend on HBeAg positive while you have to consult ifHBVDNA is detected as negative. We also found that the reinfection rate of HAV is low in HB patients with HBeAg pos-itive while the rate is high in HB patient with HBeAg negative.