期刊文献+

非小细胞肺癌放射治疗的剂量分割研究进展

Progress of dose fraction in radiotherapy for non-small cell lung cancer
下载PDF
导出
摘要 放疗是局限晚期非小细胞肺癌患者的主要治疗手段,改变不同的剂量分割方式是提高放疗疗效的手段之一。不同的剂量分割方式有不同的优缺点,当然也适用于不同的患者。我们将对非小细胞肺癌放射治疗不同的剂量分割方式作一综述。 Radiotherapy is one of the main treatment options for patients with advanced limited non small cell lung cancer. From the viewpoint of radiobiology, the change of fractionation schedule in radiotherapy might improve the therapet, tic effect. There are many different methods of fractionated irradiation: from conventional radiation including hyperfractionated radiotherapy, accelerated radiotherapy and hypofractionated radiotherapy, etc. In this paper, we summarized the definition of the different types of fractionated irradiation, and its clinical application.
出处 《中国癌症杂志》 CAS CSCD 2007年第5期402-405,共4页 China Oncology
关键词 非小细胞肺癌 放射治疗 剂量分割 non-small cell lung cancer radiotherapy dose fraction
  • 相关文献

参考文献18

  • 1Perez CA,Stanley K,Rubin P,et al.A prospective randomized study of various irradiation doses and fractionation schedules in the treatment of inoperable non-small cell carcinoma of the lung.Preliminary report by the Radiation Therapy Oncology Group[J].Cancer,1980,45:2744-2753.
  • 2Le Chevalier T,Arriagada R,Quoix E,et al.Radiotherapy alone versus combined chemotherapy and radiotherapy in nonresectable non-small-cell lung cancer:first analysis of a randomized trial in 353 patients[J].J Natl Cancer Inst,1991,83:417-423.
  • 3Bradley J,Graham MV,Winter K,et al.Toxicity and outcome results of RTOG 9311:a phase Ⅰ-Ⅱ dose-escalation study using three-dimensional conformal radiotherapy in patients with inoperable non-small-cell lung carcinoma[ J ].Int J Radiat Oncol BiolPhys,2005,61 (2):318-328.
  • 4Cox JD,Azarnia N,Byhardt RW,et al.A randomized phase Ⅰ /Ⅱ trial of hyperfractionated radiation therapy with total doses of 60.0 Gy to 79.2 Gy:possible survival benefit with greater than or equal to 69.6 Gy in favorable patients with Radiation Therapy Oncology Group stage Ⅲ non-small cell lung carcinoma:report of Radiation Therapy Oncology Group 83-11[ J ].J Clin Oncol,1990,8(9):1543-1555.
  • 5Komaki R,Scott CB,Sause WT,Johnson DH,et al.Induction cisplatin/vinblastine and irradiation vs.irradiation in unresectable squamous cell lung cancer:failure patterns by cell type in RTOG 88-08/ECOG 4588.Radiation Therapy Oncology Group.Eastern Cooperative Oncology Group[J].Int J Radiat Oncol Biol Phys,1997,39 (3):537-544.
  • 6Ball D,Bishop J,Smith J,et al.A randomised phase Ⅲ study of accelerated or standard fraction radiotherapy with or without concurrent carboplatin in inoperable non-small cell lung cancer:final report of an Australian multi-centre trial[ J ].Radiother Oncol,1999,52(2):129-136.
  • 7Saunders M,Dische S,Barrett A,et al.Continuous hyperfractionated accelerated radiotherapy (CHART) versus conventional radiotherapy in non-small cell lung cancer:a randomised multicentre trial[J].Lancet,1997,350(9072):161-165.
  • 8Saunders M,Dische S,Barrett A,et al.Continuous hyperfractionated,accelerated radiotherapy (CHART) versus conventional radiotherapy in non-small cell lung cancer:mature data from the randomised multicentre trial[J].Radiother Oncol,1999,52(2):137-148.
  • 9Kirkbride P,Hatton M,Lorigan P,et al.Fatal pulmonary fibrosis associated with induction chemotherapy with carboplatin and vinorelbine followed by CHART radiotherapy for locally advanced non-small cell lung cancer[J].Clin Oncol,2002,14 (5):361-366.
  • 10Saunders MI,Rojas A,Lyn BE,et al.Experience with dose escalation using CHARTWEL (continuous hyperfractionated accelerated radiotherapy weekend less) in non-small cell lung cancer[J].Br J Cancer,1998,78(10):1323-1328.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部