期刊文献+

慢性乙型肝炎患者肝组织瘦素的表达 被引量:3

原文传递
导出
摘要 近年来瘦素(leptin)与肝脏疾病的关系日益受到关注。动物实验表明,瘦素可能在鼠肝纤维化病理形成中具有重要意义。目前关于人瘦素血清学研究较多,而本实验采用免疫组化方法,主要探讨HBV感染者肝组织原位瘦素表达情况。
出处 《中华传染病杂志》 CAS CSCD 北大核心 2007年第3期177-178,共2页 Chinese Journal of Infectious Diseases
基金 石家庄市科学技术研究与发展指导计划项目(05120483)
  • 相关文献

参考文献5

  • 1Ikejima K, Honda H, Yoshikawa M, et al. Leptin augments inflammatory and profibrogenie responses in the murine liver induced by hepatotoxic chemicals. Hepatology, 2001, 34:288-297.
  • 2中华医学会传染病与,寄生虫病学分会,肝病学分会.病毒性肝炎防治方案[J].中华肝脏病杂志,2000,8(6):324-329. 被引量:14010
  • 3Comlekci A, Akpinar H, Yesil S, et al. Serum leptin levels in patients with liver cirrhosis and chronic viral hepatitis. Stand J Gastroenterol, 2003, 38 : 779-786.
  • 4Potter JJ, Womack L, Mezey E, et al. Transdifferentiation of rat hepatic stellate cells results in leptin expression. Biochem Biophys Res Commun, 1998,244 : 178-182.
  • 5Potter JJ, Rennie-Tankesley L, Mezey E. Influence of leptin in the development of hepatic fibrosis produced in mice by Schistosoma mansoni infection and by chronic carbon tetrachloride administration. J Hepatol, 2003, 38:281-288.

共引文献14009

同被引文献42

  • 1戚丽,路中.非酒精性脂肪肝胰岛素抵抗及血清瘦素和脂联素水平的研究[J].中国中西医结合消化杂志,2006,14(3):167-170. 被引量:5
  • 2丁效蕙,赵景民,孙艳玲,周光德,潘登,杨建法,赵雨来.非酒精性脂肪性肝炎肝组织TNF-α、TGF-β_1和Leptin的表达及意义[J].解放军医学杂志,2006,31(8):750-750. 被引量:6
  • 3Berthou F, Rouch C, Gertler A, et al. Chronic central leptin infusion differently modulates brain and liver insulin signaling [ J ]. Mol Cell Endocrinol, 2011,337 ( 1 - 2 ) : 89 - 95.
  • 4Kanzler S, Lohse AW, Keil A. et al. TGF-betal in liver fibrosis: an inducible transgenic mouse model to study liver fibrogenesis[ J]. Am J Physiol,1999 ,276(4) : 1059 -1068.
  • 5Kothary PC, Badhwar J, Weng C, et al. Impaired Intracellular Signaling May Allow Up-Regulation of CTGF-Synthesis and Secondary Peri-Retinal Fibrosis in Human Retinal Pigment Epithelial Cells from Patients with Age-Related Macular Degeneration [ J]. Adv Exp Med Biol, 2010,664:419 - 428.
  • 6Sobrevals L, Rodriguez C, Romero-Trevejo JL, et al. Insulin- like growth factor I gene transfer to cirrhotic liver induces fibrolysis and reduces fibrogenesis leading to cirrhosis reversion in rats[JJ. Hepatology,2010, 51(3) :912 -921.
  • 7Ruddell RG, Hoang-Le D, Barwood JM, et al. Ferritin functions as a proinflammatory eytokine via iron-independent protein kinase C zeta/nuclear factor kappaB-regulated signaling in rat hepatic stellate cells~ J]. Hepatdogy,2009,49 (3) :887 - 900.
  • 8Zhang Y, Proenca R, Maffci M, et al. Positional cloning of the mouse obese gene and its human homologue[ J]. Nature, 1994, 372:425 - 432.
  • 9卢建华,赵文伟,段毅力,刘勇钢,钱静.病毒性肝炎合并肝组织脂肪变性患者肝组织瘦素表达研究[J].河北医药,2007,29(7):676-677. 被引量:1
  • 10World Health Organization. Hepatitis B. World Health Organization Fact Sheet 204 dex, 2000-10, cited 2008-04; 1(1): 24 screens. Available from: URL: http://www.who.int/mediacentre/factsheets/fs204/en/in html

引证文献3

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部