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丙型肝炎病毒受体研究现状及展望

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摘要 在HCV感染宿主过程中,病毒首先结合到靶细胞表面,经受体介导进入细胞,然后才能复制、表达病毒蛋白并引起相关的病理变化。因此,HCV宿主细胞表面的受体或辅助受体的研究显得尤为重要。目前难以从感染的血清和组织中分离天然HCV病毒颗粒,此外缺乏有效的体外病毒复制系统和小动物模型,所以,HCV宿主细胞表面受体及HCV感染靶细胞机制仍不太清楚。
出处 《中华传染病杂志》 CAS CSCD 北大核心 2007年第3期189-192,共4页 Chinese Journal of Infectious Diseases
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