无梗五加叶化学成分的研究

Chemical constituents in the leaves of Acanthopanax sessiliflorus

目的：研究无梗五加叶的化学成分。方法：利用各种色谱技术进行分离纯化，根据理化常数和光谱数据等进行结构鉴定。结果：从无梗五加叶中分得两种化合物，其结构分别鉴定为：Ⅰ，（１Ｒ）１，１１α二羟基３，４开环羽扇豆４（２３），２０（２９）二烯３，２８二酸３，１１内酯２８氧αＬ吡喃鼠李糖基（１→４）βＤ吡喃葡萄糖基（１→６）βＤ吡喃葡萄糖苷；Ⅱ，β谷甾醇。结论：化合物Ⅰ系首次从该植物中分出，并且为主要成分。

OBJECTIVE:To study the chemical constituents in the leaves of Acanthopanax sessiliflorus.METHODS:Various kinds of chromatography and structure elucidation were used to separate and purify the constituents,and physical and chemical constants and spectral data were measured.RESULTS:Two compounds were isolated from the leaves of Acanthopanax sessiliflorus.Their structures were identified as:Ⅰ,(1R) 1,11α dihydroxy 3,4 seco lupa 4(23),20(29) diene 3,28 dioic acid 3,11 lactone 28 O α L rhamnopyranosyl(1→4) β D glucopyranosyl(1→6) β D glucopyranoside;Ⅱ,β sitosterol.CONCLUSION:Compound Ⅰ,first isolated from this plant,is the main constituent of the leaves of this plant.