二异丙酚注射液在小儿胃镜检查中的镇静作用

Propofol Sedation during Gastroscopy in Children

目的研究适合儿童胃镜检查的镇静方法。方法150例患儿随机分为A组(二异丙酚组)和B组(盐酸瑞芬太尼+二异丙酚组)。观察患儿镇静起效时间、苏醒时间、血压、心率、呼吸、血氧饱和度变化及对患者反应,并进行术后满意度调查。结果二组均取得良好的镇静效果及满意度,使用二异丙酚前先用盐酸瑞芬太尼可减轻推注二异丙酚引起的疼痛感,减少二异丙酚用量,从而缩短术后苏醒时间。结论儿童胃镜检查中应用二异丙酚可起到安全、有效镇静的效果,复合盐酸瑞芬太尼效果更佳。

Objective To study the method of sedation for gastroscopy in children. Methods One hundred and fifty children were randomly divided into group A （ propofol group） and group B （ propofol ＋ remifentanil group）. The action time of sedation, recovery time, blood pressure, heart rate, respiratory rate, oxygen saturation and children＇s reaction were observed. These patients＇ satisfaction were investigated after gastroscopy. Results Good sedation effect and high rates of patients＇ satisfaction were achieved in both groups. Bolus of remifentanil before giving propofo could relieve pain caused by bolus of propofol,decreased the close of propofol and shorten the recovery time. Conclusion These results show that propofol is safe and effective in gastrocopy of childrcn;propofol combinating remifentanil can get better sedation effect.