口腔鳞癌术后复发相关因素的临床研究

A clinical research on the postoperative recurrentive factors of oral squamous cell carcinoma

目的:研究分析影响口腔鳞癌预后的临床病理因素。方法:对673例原发口腔鳞癌患者以病变部位、肿瘤生长类型、临床T分期、局部淋巴结转移、治疗方式、术后病理分级以及下颌骨切除方式等指标来研究与口腔鳞癌预后相关的因素。结果:口腔鳞癌术后的复发率与病变部位、肿瘤的生长类型、肿瘤的T分期、区域淋巴结转移及病理分级等因素有关,与治疗方式及颌骨切除方式等因素无关。结论:临床工作中,我们应综合分析各种临床病理因素。对与术后复发率关系较为密切的因素要进行仔细评估,制定出有效的预防措施,提高口腔鳞癌的手术治愈率及生存率。

Objective：To analyze the postoperative recurrentive factors of oral squamous cell carcinoma. Methods： 673 patients of primary oral squamous cell carcinoma were involved. The focus location, growth type, T stage, lymphonodus metastasis, treatment, pathological grading anti resection mode of mandible were evaluated to determine the prognosis of patients. Results： The postoperative recurrence rate was relevant to the focus location, growth type, T stage, lymphonodus metastasis anti pathological grading, while the treatment anti resection mode of mandible had no effects on the recurrence rate. Conclusion： It＇s of great importance to estimate all kinds of clinicopathologie factors and perform preventive treatments during the clinical work to promote the operative cure rate anti survival rate of patients with oral squamous cell carcinoma.