色氨酸耗竭试验对人体生理功能、认知功能及精神疾病的影响
摘要
色氨酸耗竭(tryptophandepletion,TD)试验,是研究中枢5.羟色胺(5-HT)功能紊乱在精神疾病发病机制中的重要而可靠的技术方法,上世纪70年代首次应用于临床研究。由于色氨酸作为5-HT前体物质,经耗竭试验后体内浓度显著下降,故TD可为研究体内5-HT浓度减低时对机体生理功能、认知功能及精神症状的作用及意义提供先决条件。
出处
《中华精神科杂志》
CAS
CSCD
北大核心
2007年第2期126-128,共3页
Chinese Journal of Psychiatry
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