摘要
G蛋白偶联受体(Gprotein-coupled receptors,GPCRs)是具有7个跨膜螺旋的蛋白质受体,是人体内最大的蛋白质家族。按GPCRs一级结构的同源性,主要分为A、B、C三族;按氨基酸序列的相似性以及与配基的结合情况GPCRs可以分为5个亚家族。本文就GPCRs的结构、分类、GPCRs的二聚化以及其固有活性等方面做了一些介绍。
G protein-coupled receptor, which is a seven transmembrane helix protein receptor, is the largest protein family in human body. By homologous of the GPCRs primary structure, it can be divided into three races. They are A.B .C races. According to the sequence similarity of amino acid and the genin union situation, GPCRs can be divided into five subfamilies, This article mainly introduces the structure, classification, dimerization and its inherent activity of GPCRs and so on.
出处
《科技信息》
2007年第11期10-11,共2页
Science & Technology Information
关键词
G蛋白偶联受体
二聚化
固有活性
G protein-coupled receptor
Dimerization
Inherent activity
