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体外诱导细胞转化为胰岛细胞的研究进展

Research Advancement of Inducing Cells to Differentiate into Islet Cells in Vitro
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摘要 巢素蛋白(nestin)阳性细胞、成体干细胞(包括间充质干细胞和胰腺导管上皮细胞)和胚胎干细胞是常用的体外诱导转化为胰岛细胞的种子细胞,本文就这三类细胞的来源、实验方法及实验结果的研究进展进行综述。 Nestin -positive cells, adult stem cells （including mesenchymal stem cells and pancreatic ductal Ep cells） and embryonic stem cells are the seed cells to be induced to islet cells. This artical reviewed in detail on the research advancement of their sources, experimental methods and results.
作者 肖乐 曹建彪
机构地区 中国人民解放军第二军医大学北京临床医学院
出处 《中国全科医学》 CAS CSCD 2007年第10期847-849,共3页 Chinese General Practice
关键词 巢素蛋白阳性细胞 间充质干细胞 胰腺导管上皮细胞 胚胎干细胞 Nestin- positive cells Mesenchymal stem cells Pancreatic ductal cells Embryonic stem cells
分类号 R587 [医药卫生—内分泌]
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参考文献18

  • 1Hunziker E,Stein M.Nestin-expressing cells in the pancreatic islets of langerhans[J].Biochem Biophys Res Commun,2000,271:116.
  • 2Lumelsky N,Blondel O,Laeng P,et al.Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets[J].Science,2001,292:1389.
  • 3田井琦,白日星,孙立波,张海燕,李卫红,介建政,张德恒.成年大鼠非胰岛内Nestin阳性细胞的体外分离、培养及分化[J].吉林大学学报（医学版）,2005,31(2):275-277. 被引量：3
  • 4Wski ZH,Abraham EJ,Gerlach MJ,et al.Multipotential nestin positive stem cells isolated from adult pancreatic islets differentiate exvivo into pancreatic endocrine,exocrine,and hepatic phenotypes[J].Diabetes,2001,50:521.
  • 5Humphrey RK,Bucay N,Beattie GM,et al.Characterization and isolation of promoter-defined nestin-positive cells from the human fetal pancreas[J].Diabetes,2003,52:2519.
  • 6陈燊,胡江,李凌松.人胚胎胰腺源nestin阳性细胞的快速获取[J].华中科技大学学报（医学版）,2004,33(2):129-131. 被引量：2
  • 7Jahr H,Bretzel RG.Insulin-positive cells in vitro generated from rat bone marrow stromal cells[J].Transqlant Proc,2003,35:2140-2041.
  • 8Oh SH,Muzzonigro TM,Bae SH,et a1.Adult bone marrowderived cells transdifferentiating into insulin-producing cells for the treatment of type I diabetes[J].Laboratory Investigation,2004,84:607-617.
  • 9Tang DQ,Cao LZ,Burkhardt BR,et al.In vivo and in vitro characterization of insulin-producing cells obtained from murine bone marrow[J].Diabetes,2004,53:1721-1732.
  • 10李艳华,白慈贤,谢超,陈琳,裴雪涛.成人骨髓间充质干细胞体外定向诱导分化为胰岛样细胞团的研究[J].自然科学进展,2003,13(6):593-597. 被引量：42

二级参考文献61

  • 1白日星,田井琦,张海燕,李卫红,孙立波,张德恒,宋茂民.新生鼠胰岛干细胞分离、培养和分化的实验研究[J].中国普通外科杂志,2004,13(10):746-749. 被引量：7
  • 2Sachs D H, et al. New islets from old. Nature (Medicine), 2000,6 : 250.
  • 3Assady S, et al. Insulin production by human embryonic stem cell.Diabetes, 2001, 50:1691.
  • 4Lumelsky N, et al. Differention of embryonic stem cells to insulin-secreting structures similar to pancreatic islets. Science, 2001,292:1389.
  • 5Zulewski H, et al. Multipotential nestin-positive stem cells isolated from adult pancreatic endocrine, exocrine and hepatic phenotypes.Diabetes, 2001, 50:521.
  • 6Woodlbury D, et al. Adult rat and human bone marrow stromal cells differentiate into neurons. Journal of Neuroscience Research, 2000,61 : 364.
  • 7Le Douarin N M. On the origin of pancreatic endocrine cells. Cell,1988, 53:169.
  • 8Schudiner M, et al. Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells. Proc Natl Acad Sci USA, 2000, 97:11307.
  • 9Smith P K, et al. Measurement of protein using bicinchoninic acid.Anal Biochem, 150:76.
  • 10Reynolds B A, et al. Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell. Dev Biol, 1996, 175:1.

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中国全科医学
2007年 第10期

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