摘要
目的:比较显微内窥镜下椎间盘除术(MED)及MED与胶原酶溶核术(CCNL)联合应用治疗腰椎间盘突出症的临床疗效。方法:120例腰椎间盘突出症患者中,60例单纯行MED治疗(MED组),另60例在行MED的基础上向椎间盘内注射胶原酶600U(MED+CCNL组)。术后观察并分析两组的疗效及并发症。结果:两组均顺利完成手术,未发生并发症。术后全部病例随访6~48个月,按照MacNab标准评定,MED组有效率为83.3%,MED+CCNL组为95%,后者明显高于前者(P<0.05)。结论:MED与CCNL联合治疗腰椎间盘突出症较单纯MED治疗具有更好的疗效。
Objective:To study the clinical effect in the treatment of lumbar disc herniation with microendoscopic discectomy(MED) and MED combining with collagenase chemonucleolysis(CCNL).Method: 120 patients with lumbar disc herniation were divided into two groups and half of them were and treated by single MED (MED group) or MED combined with CNLL(MED+CNLL group).MED procedures were performed with conventional ways,and following MED 600U of collagenase were injected into the lumbar disc.The efficiency anti complications of all cases were investigated after operation.Result:All cases were followed up for 6-48 months,according to MacNab evaluation criterion,the rate of efficency:single MED group was 83.3% anti MED+CNLL group was 95%,the latter was significantly higher than the former (P〈0.05).Conclusion:MED combined with CCNL is more effective in the treatment of lumbar disc herniation with wide clinical indications and quick recovery.
出处
《中国脊柱脊髓杂志》
CAS
CSCD
2007年第5期354-356,共3页
Chinese Journal of Spine and Spinal Cord