儿童食管炎236例临床分析

Clinical features of esophagitis in 236 children

目的探讨儿童食管炎的发病、临床特征、内镜检查、黏膜病理及其诊断与治疗。方法对236例诊断为食管炎患儿的病史、内镜检查、部分黏膜病理情况进行分析。结果8500例胃镜检查患儿中,诊断为食管炎236例(2.8%)。食管炎病例中,黏膜病理以慢性炎症为主。不同年龄儿童食管炎的临床特点为:30例0～1岁患儿表现为呕吐、厌食1.8%(30/236例);92例～5岁患儿临床除呕吐、厌食还出现腹痛13.6%(92/236例);114例～13岁患儿临床表现为恶心、腹痛48.3%(114/236例)。结论儿童食管炎患者黏膜病理以慢性炎症为主,不同年龄食管炎患者临床表现不同,治疗方案应个体化。

Objectives To study the clinical manifestations, endoscopic features, pathologic changes in tuniea nmcosa, diagnosis and treatment of esophagitis in children. Methods Clinical manifestations and endoscopic features of 236 children with esophagitis were studied. Biopsy was applied in a part of these patients. Results 236 （2.8%） patients were diagnosed as esophagitis from 8 500 cases examined by gastroscope. Chronic inflammation was the major pathologic change in these children with esophagitis. There were differences between ages in clinical manifestation of esophagitis： vomiting and anorexia were found in 30 infants, while 92 cases aged from 2 to 5 years presented abdominal pain besides vomiting and anorexia; nausea and abdominal pain appeared in 114 cases aged from 6 to 13 years. Conclusions The incidence of esophagitis in preschoolers and school children is significantly higher than that in infants. Other upper gastrointestinal diseases were found in all the preschoolers and school children with esophagitis, while only 5 in 30 cases of toddler （1.6%）. Children with vomiting, anorexia and abdominal pain should be examined by endoscope if necessary to get proper and individual treatment.