摘要
目的:通过HRCT的表现来揭示慢性阻塞性肺疾病(COPD)的病理进程,为临床及早干预及选择治疗方案提供依据。方法:分析96例临床确诊的COPD病例的HRCT表现与56例无COPD病史的外伤病例作对照,从中央气道病变,外周气道病变,肺实质病变及肺血管病变等四方面来评估COPD的病理学改变。结果:COPD的中央气道T,T/D,Ai,WA%及TI等指标与对照组比较,差异有显著性(P<0.01),外周气道的显示率,肺气肿及“马赛克灌注”的发生率均较对照组高,经统计学检验,差异有显著性(P<0.01)。结论:HRCT可以从影像学角度反映COPD的病理改变,结合肺功能检查,可更准确地揭示COPD的病程发展,从而为临床选择治疗方案提供客观依据。
Objective: We expect to reveal COPD pathologic progress through HRCT performance, which is to provide a basis for the early interference and the choice of therapeutic schedule. Methods: To analyze the performance of 96 clinical definite diagnosis and compare the 96 cases above with 56 external injury cases without COPD disease history , we can find four kinds of changes on HRCT,that is: the central airway pathological changes, the surface airway pathological changes, the lung substance pathological changes and lung bloed-vessel pathological changes, which can be used to evaluate COPD pathologic changes. Results:Tile difference of the central airway indext T.T/D, Ai, WA% and TI between the subjects has been shown by statistics ( P 〈 0.01), the manifestation rate of surface airway,the occurrence rate of emphysema and "the mosaic infusion" is higher than the contrast group with the notable diffirence by statistics ( P 〈 0.01). Conclusion:The pathologic changes of COPD can be kown through HRCT performance, together with the check of lung function, by learning the development of illness. We can have a better choice for the clinical therapetitic schedule.
出处
《医学影像学杂志》
2007年第4期357-359,共3页
Journal of Medical Imaging
基金
浙江省嘉兴市科技局资助项目(2005AY3060)