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胃癌细胞血管内皮生长因子RNA干扰对血管内皮细胞生长的影响 被引量:1

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摘要 目前抗肿瘤血管生成的研究多在动物模型中进行,这样虽然可以模拟肿瘤生长的微环境,但由于受到体内环境诸多因素的影响,促血管生成因子人为表达降低后,血管内皮细胞的生物学行为发生了哪些变化难以明确。采用分泌促血管生成因子的肿瘤细胞与血管内皮细胞共培养可以初步明确这一问题。本研究采用RNA干扰(RNAi)技术观察其抑制肿瘤细胞血管内皮生长因子(VEGF)表达后对血管内皮细胞生长的影响。
出处 《中华消化杂志》 CAS CSCD 北大核心 2007年第4期278-280,共3页 Chinese Journal of Digestion
基金 山东省科技厅优秀中青年科学家科研奖励基金资助课题(2005BS02013)]
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