头孢克肟治疗Ⅱ型前列腺炎的初步观察

Preliminary observation on cefixime in treating chronic bacterial prostatitis

目的评价头孢克肟片治疗慢性细菌性前列腺炎的临床疗效和安全性。方法采用前瞻仰性随机平行对照临床研究,应用头孢克肟治疗慢性细菌性前列腺炎39例,并以司帕沙星治疗42例作对照。结果试验组治愈32例(82.1%),对照组治愈28例(66.7%)。试验组中未见任何不良反应,对照组中7例(16.7%),两组间比较治愈率、有效率差异无统计学意义(P>0.05),不良反应发生率差异有统计学意义(P<0.05)。结论头孢克肟治疗细菌性前列腺炎的临床疗效与对照组(司帕沙星组)相当,而不良反应则明显低于对照组,值得在临床上推广应用。

Objective To evaluate clincal curative effect and safety of cefixime in treating chronic bacterial prostatitis. Methods Applyed prospective trabant parallel comparative clinical research, adopted cefixime to treat 39 chronic bacterial prostatis patients and adopted sparfloxacin to treat 42 chronic bacterial prostatis patients to compare. Results Thirty - two （82%） patients were cured in the experimental group and 28 （67%） patients were cured in the control group. Nobody had adverse effect in the experimental group and 7 （ 16. 7% ） patients had adverse effect in the control group. Cure rate and efficient had no significant difference between two groups （ P 〉 0. 05 ）. Incidence rate of adverse effect had significant differences between two groups （P 〈 0. 05 ）. Conclusion Clinical curative effect has not significant difference between two groups. Adverse effect in the experimental group is obviously lower than that in the control group.