肺癌术后呼吸衰竭高危因素分析

Factor analysis of respiratory failure after resection of lung cancer

目的探讨肺癌术后发生呼吸功能衰竭（呼衰）的危险因素。方法对1997年1月-2006年10月间完成的512例肺癌切除术后发生呼衰的22例患者的临床资料进行分析。结果大于60岁（18例）、长期吸烟（14例）的患者术后呼衰发生率明显增高；全肺切除术后呼衰明显高于肺叶切除和肺楔形切除；术前VC、MVV、FEV1％≥60％的患者术后呼衰明显低于〈60％患者。结论预测肺癌术后呼衰的发生可根据年龄、吸烟指数、术前肺功能及手术方式来综合判断，并可针对性的采取预防措施，减少呼吸功能衰竭的发生。

Objective To analyze the reasons of respiratory failure after resection of lung cancer. Methods Clinical data of 22 patients with respiratory failure in 512 patients after resection of lung cancer from January of 1997 to October of 2006 were analyzed. Results The patients（age〉60,18 cases）and those with long smoking history（14 cases） were easy to develop respiratory failure;the whole pneumonectomy was more dangerous than pulmonary lobectomy and wedge-shape excision of lung. Before operation,patients with VC,MVV and FEV1%≥60 % were less dangerous than those〈60%. Conclusion By the age and smoke-index,the pulmonary fuction before resection and the operation program, we can forecast respiratory failure after resection of lung cancer. Through taking preventive measures, we can reduce the development of respiratory failure.