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罗格列酮联合胰岛素治疗2型糖尿病临床疗效分析 被引量:1

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摘要 目的探讨胰岛素增敏剂罗格列酮联合胰岛素治疗2型糖尿病的临床疗效。方法49例大剂量胰岛素治疗的2型糖尿病患者,加服马来酸罗格列酮4 mg/d,进行为期24周的用药观察。结果与治疗前比较:空腹及餐后血糖均明显下降(P<0.05),糖化血红蛋白也下降0.9%(P<0.05),胰岛素用量减少14 U(P<0.05)。结论2种药物联合应用可使高血糖得到满意控制,同时可以改善胰岛β细胞功能,降低胰岛素抵抗,增加胰岛素敏感性,减少胰岛素用量,二者起协同作用。
作者 叶飞 邓月珍
出处 《徐州医学院学报》 CAS 2007年第5期325-327,共3页 Acta Academiae Medicinae Xuzhou
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同被引文献5

  • 1李忠梅,荣维,李伟,祁立子.诺和锐强化治疗2型糖尿病临床体会[J].辽宁实用糖尿病杂志,2004,12(4):40-41. 被引量:6
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  • 3Strowig SM, Raskin P. Combination therapy using metformin orthiazolidinediones and insulin in the treatment ofdiabetesmellitus [J].DiabetesObesMetab, 2005, 7(6) : 633-641.
  • 4HartungDM, TouchetteDR, BultemeierNC, eta.l Risk of hosptalization for heart failure associated with thiazolidinedione therapy: amedicaid claims-based case-control study[J].Pharm acotherapy, 2005, 25 (10): 1329-1336.
  • 5李金荣,蓝海,覃丽娜,莫燕燕,李睿懿.罗格列酮联合胰岛素治疗老年2型糖尿病的临床研究[J].蛇志,2008,20(2):113-114. 被引量:2

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