摘要
采用[3+2]1,3-偶极环加成反应,苯炔前体邻-三甲硅基苯酚三氟甲磺酸酯在氟化铯的作用下与硝酮反应合成了9个2,3-二取代苯并[d]异噁唑烷,收率87%~97%。其结构经1H NMR,13C NMR和高分辨率MS确证。
In the presence of cesium fluoride, nine 2, 3-disubstituted benzo [ d ] isoxazolidines in yields of 87% -97% were prepared by 1,3-dipolar [3 + 2] cycloaddition reaction between aryne precursor o-trimethylsilylphenyl triflate and a series of nitrones. Their structures were characterized by ^1H NMR, ^13C NMR and high resolution MS.
出处
《合成化学》
CAS
CSCD
2007年第3期292-295,共4页
Chinese Journal of Synthetic Chemistry