间氯磺酰基苯甲酰氯的合成

Synthesis of m-Chlorosulfonylbenzoyl Chloride

三氯甲苯和氯磺酸反应制备了间氯磺酰基苯甲酰氯。反应的最佳条件为:三氯甲苯10 mL(70 mmol),n(三氯甲苯)∶n(氯磺酸)=1∶2,于120℃反应2 h。在最佳反应条件下,收率达81%。

m-Chlorosulfonylbenzoyl chloride were prepared by the reaction of benzotrichloride with chlorosulfonic acid. The optimum reaction conditions at 120 ℃ for 2 h were as follows ： benzotrichloride was 10 mL（70 mmol） ; n（benzotrichloride） ： n（ chlorosulfonic acid） = 1：2. The yield was 81% under the optimum reaction conditions.