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生物芯片在胃癌药物病理学研究中的先导作用 被引量：3

Guiding role of biomicroarray in pharmaco-pathology of gastric cancer
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摘要 生物芯片是后基因组时代医学研究中的重要手段,其在转录组、蛋白质组与肿瘤功能基因组研究中的作用日益突出。基因芯片、蛋白芯片与组织芯片构成了生物芯片的主体,该技术有望在胃癌特异性标志物发现上发挥作用。药物病理学是临床病理学领域的新兴分支学科,其主要工作是利用病理学手段识别肿瘤组织存在的分子靶点,为临床针对性靶向治疗提供用药依据。 Biomicroarray is an important technique in the medical research at postgenome era, especially in the transcriptomic, proteomic and oncogenomic research. Biomicroarray is mainly composed of gene microarray, protein microarray and tissue microarray, which may function in identifying tumor-specific markers for gastric cancer. Pharmaco-pathology is a novel branch in clinical pathology, whose main work is identifying molecular targets on tumor tissues by pathological methods and supplying evidence for targeted drug therapy.
作者 于颖彦
机构地区 上海交通大学医学院瑞金医院外科上海消化外科研究所
出处 《上海交通大学学报（医学版）》 CAS CSCD 北大核心 2007年第5期491-493,共3页 Journal of Shanghai Jiao tong University:Medical Science
基金 上海市科委重点基础研究项目(05JC14013) 上海市卫生局基金(05-Ⅲ-005-020)~~
关键词 蛋白芯片 组织芯片 药物病理学 胃癌 肿瘤标志物 protein microarray tissue microarray pharmaco-pathology gastric cancer tumor markers
分类号 R735.2 [医药卫生—肿瘤]
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参考文献8

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二级参考文献19

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共引文献5

同被引文献47

  • 1吴俊,史宏灿.生物芯片在肺癌中的运用现状及其进展[J].国际外科学杂志,2007,34(2):97-101. 被引量：1
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引证文献3

二级引证文献3

上海交通大学学报（医学版）
2007年 第5期

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