期刊文献+

Predictors of post coronary artery bypass grafting atrial fibrillation 被引量:5

Predictors of post coronary artery bypass grafting atrial fibrillation
下载PDF
导出
摘要 Objective: To investigate the incidence and relative risk factors of post coronary artery bypass grafting(post-CABG) atrial fibrillation (AF). Methods: 312 patients with CABG were reviewed and divided into an AF group and a non-AF group. Statistical analysis was used to compare the data between the two groups and screen for risk factors of post-CABG AF. Results: 103/312 (33.01%) patients developed post-CABG AF. Univariate analysis showed that patients in AF group compared with those in non-AF group were more likely to have advanced age (≥ 70 years), early postoperative withdrawal of β-blockers, hypertension, left atrial enlargement (≥40 mm), a history of AF, prolonged p-wave duration (≥ 120 ms) and increased number of grafts (≥13). Multivariate logistic regression analysis showed that advanced age (≥70 years), early postoperative withdrawal of β-blockers, hypertension, left atrial enlargement (≥40 mm) and a history of AF were highly related to post-CABG AF. Conclusion: The incidence of AF in patients following CABG was 33.01% in this study. Advanced age, early postoperative withdrawal of 13-blockers, hypertension, left atrial enlargement and a history of AF were independent risk factors of post-CABG AF. Objective: To investigate the incidence and relative risk factors of post coronary artery bypass grafting(post-CABG) atrial fibrillation (AF). Methods: 312 patients with CABG were reviewed and divided into an AF group and a non-AF group. Statistical analysis was used to compare the data between the two groups and screen for risk factors of post-CABG AF. Results: 103/312 (33.01%) patients developed post-CABG AF. Univariate analysis showed that patients in AF group compared with those in non-AF group were more likely to have advanced age (≥ 70 years), early postoperative withdrawal of β-blockers, hypertension, left atrial enlargement (≥40 mm), a history of AF, prolonged p-wave duration (≥ 120 ms) and increased number of grafts (≥13). Multivariate logistic regression analysis showed that advanced age (≥70 years), early postoperative withdrawal of β-blockers, hypertension, left atrial enlargement (≥40 mm) and a history of AF were highly related to post-CABG AF. Conclusion: The incidence of AF in patients following CABG was 33.01% in this study. Advanced age, early postoperative withdrawal of 13-blockers, hypertension, left atrial enlargement and a history of AF were independent risk factors of post-CABG AF.
出处 《Journal of Nanjing Medical University》 2007年第3期139-142,共4页 南京医科大学学报(英文版)
基金 This study was supported by 135 foundation of Jiangsu province
关键词 coronary artery bypass grafting atrial fibrillation risk factors coronary artery bypass grafting atrial fibrillation risk factors
  • 相关文献

参考文献10

  • 1Guo Y,Hu SS,Wu QY,Xu JP,Song YH,Zhu XD.Predic- tors of atrial fibrillation after coronary artery bypass graft surgery[].Chinese Medical Journal.2002
  • 2Chandy J,Nakai T,Lee RJ,Bellows WH,Dzankic S,Leung JM.Increases in P-wave dispersion predict postoperative atrial fibrillation after coronary artery bypass graft surgery[].Anesthesia and Analgesia.2004
  • 3Manning WJ,Gelfand EV.Left atrial size and postoperative a- trial fibrillation: the volume of evidence suggests it is time to break an old habit[].Journal of the American College of Cardiology.2006
  • 4Taylor AD,Groen JG,Thorn SL,Lewis CT,Marshall AJ.New insights into onset mechanisms of atrial fibrillation and flutter after coronary artery bypass graft surgery[].Heart.2002
  • 5Kerstein J,Soodan A,Qamar M,Majid M,Lichstein E,Hol- lander G,et al.Giving IV and oral amiodarone perioperatively for the prevention of postoperative atrial fibrillation in patients undergoing coronary artery bypass surgery: the GAP study[].Chest.2004
  • 6Pedersen OD,Bagger H,Kober L,Torp-Pedersen C.Tran- dolapril reduces the incidence of atrial fibrillation after acute myocardial infarction in patients with left ventricular dysfunc- tion[].Circulation.1999
  • 7White HD,Antman EM,Glynn MA,Collins JJ,Cohn LH,Shemin RJ,et al.Efficacy and safety of timolol for prevention of supraventricular tachyarrhythmias after coronary artery by- pass surgery[].Circulation.1984
  • 8Banach M,Rysz J,Drozdz JA,Okonski P,Misztal M,Baryl- ski M,et al.Risk factors of atrial fibrillation following coronary artery bypass grafting: a preliminary report[].Circulation Journal.2006
  • 9Hakala T,Pitkanen O,Hippelainen M.Feasibility of predicting the risk of atrial fibrillation after coronary artery bypass surgery with logistic regression model[].Scand J Surg.2002
  • 10Halpin LS,Barnett SD,Burton NA.National Databases and Clinical Practice Specialist: Decreasing Postoperative Atrial Fibrillation Following Cardiac Surgery[].Outcomes Management.2004

同被引文献18

  • 1Castro L,Mialet-Perez J,Guilleneau A,et al. Differential functional effects of two 5-HT4 receptor isoforms in adult cardiomyocytes [ J ]. J Mol Cell Cardiol, 2005,39 (2), 335 - 344.
  • 2Armelle Pindon,Geert Van Hecke,Paul Van Gompel,et al. Differences in signal transduction of two 5-HT4 receptor splice variants:Compound specificity and dual couphng with Gs-and Gi/o-Proteins[J]. Mol Pharmacol, 2002,61(1) : 85-96.
  • 3Trond Brattelid,Ane M Kvingedal,Kurt A Krobert,et al. Cloning,pharmacological characterisation and tissue distri- bution of a novel 5-HT4 receptor splice variant,5-HT4 (i) [J]. Naunyn-Sehmiedeberg's Arch Ph armaeol, 2004,369 (6) :616-628.
  • 4Emmanuella Di Scala,Ste'phanie Rose,Olivier He'rauh, et al. Conformatinnal state of human cardiac 5-HT4(g)receptors influences the functional effects of polyclonal anti- 5-HT4 receptor antibodies[J]. Biochemical Pharmacology, 2007,73(7) :964-971.
  • 5Davide Pau,Antony J Workman,Kathleen A Kane,et al. Electrophysiological effects of 5-hydroxytryptamine on isolated human atrial myocytes,and the influence of chronic β-adrenoceptor blockade[J]. British Journal of Pharmacology, 2003,140(8) : 1434-1441.
  • 6Giuseppe Lonardo, Elisabetta Cerbai, Simona Casini,et al. Pharmacological modulation of the hyperpolarization-activated current (If)in human atrial myocytes:focus on G protein-coupled receptors [J]. Journal of Molecular and Cellular Cardiology, 2005,38 (3) : 453-460.
  • 7Alberto J Kaumann,Finn Olay Levy. 5-Hydroxytryptamine receptors in the human cardiovascular system[J]. Pharmacology & Therapeutics, 2006,111 (3) : 674-706.
  • 8Frank Lezoualc'h, Klaudia Steplewski, Laura Sartiani, et al. Quantitative mRNA analysis of serotonin 5-HT4 receptor isoforms,calcium handling proteins and ion channels in human atrial fibrillation[J]. Biochemical and Biophysical Research Communications, 2007,357 ( 1 ) : 218-224.
  • 9Hirosbi Watanabe, Naohito Tanabe,Toru Watanabe, et al. Metabolic syndrome and risk of development of atrial Fibrillation: the niigata preventive medicine study [J]. Circulation, 2008, 117(10) : 1255-1260.
  • 10Task Force Members,Valentin Fuster,Lars E Ryden,et al. ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation-executive summary[J]. European Heart Journal, 2006,27(16) : 1979-2030.

引证文献5

二级引证文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部