芦荟多糖对肝癌细胞及外周血单个核细胞作用的研究

Study on the Effect of Aloe Polysaccharide on Primary Hepatic Carcinoma Cell and Peripheral Blood Monouclear Cell

目的:探讨芦荟多糖抑制肝癌细胞生长的作用机制。方法:采用四氮唑盐法(MTT)法检测不同浓度的芦荟多糖对体外培养的原发性肝癌细胞(PHCC)与自体外周血单个核细胞(PBMC)生长的影响。结果:芦荟多糖可不同程度地抑制肝癌细胞的生长,促进外周血单个核细胞的生长,并且呈浓度依赖性。结论:芦荟多糖可提高机体的免疫力以达到抑制肿瘤生长的作用,并在一定程度上可直接抑制体外肿瘤细胞的生长。

Objective： To study the inhibition mechanism of aloe polysaccharide（AP）on the liver cancer cell growth. Method： By using the MTT method to study the effect of AP on the growth of primary hepatic carcinoma cell（PHCC） and peripheral blood monouclear cell（PBMC）. Result： In some extent AP can inhibit the PHCC growth and enhance the PBMC growth and the effect. Conclusion： AP can improve the immunity and accordingly inhibit the growth of PHCC. In some extent the AP can directly inhibit the growth of PHCC.