摘要
目的:观察黄芪当归合剂治疗糖尿病患者的临床疗效。方法:分别用黄芪当归合剂(治疗组32例)和科素亚(对照组22例)治疗糖尿病肾病患者,疗程均为3个月,并比较两组治疗前后的临床症状,血糖水平、脂质代谢,尿蛋白等,观察黄芪当归合剂的治疗效果。结果:总有效率治疗组为80.9%,对照组为63.6%。治疗组治疗后在临床症状、尿蛋白、尿白蛋白和脂质代谢等方面均较治疗前有明显改善(P<0.05);对照组仅尿白蛋白一项治疗后有改善(P<0.05),其余指标治疗前后比较差异无显著性。结论:黄芪当归合剂具有减少24 h尿蛋白,尿白蛋白、改善餐后血糖和脂质代谢等作用。
AIM： To observe the effect of Huangqi Danggui Mixture on diabetic nephropathy. METHODS： Using Huangqi Danggui Mixture to treat 32 patients with diabetic nephropathy, In control group 22 patients were treated with Losartan. The therapeutic course was 3 months for both groups. The changes of clinical symptoms, blood glucose, lipid metabolism and urinary albumin were observed and compared. RESULTS： The total effective rate in the treated group was 80.9% while in the control group 63.3%. The symptoms, urinary protein and albumin as well as lipid metabolism in the treated group all significantly improved after treatment （ P 〈 0.05 ）, but in the control group improvement only showed in urinary albumin level （ P 〈 0.05 ）. CONCLUSION： Huangqi Danggui Mixture has the effects on reducing urinary protein in 24 h, lowering urinary albumiun, improving blood glucose after meal and lipid metabolism.
出处
《中成药》
CAS
CSCD
北大核心
2007年第5期641-644,共4页
Chinese Traditional Patent Medicine
关键词
黄芪当归合剂
糖尿病肾病
科素亚
Huangqi Danggui Mixture
diabetic nephropathy
Losartan
