口服枸橼酸铁铵MRCP诊断低位梗阻性黄疸的价值

Oral ferric ammonium citrate solution in MRCP for diagnosing low-level obstructive jaundice

目的:评价口服枸橼酸铁铵MRCP在低位梗阻性黄疸诊断中的应用价值。方法:对36例拟诊低位梗阻性黄疸的病人行口服枸橼酸铁铵前后MRCP及常规胆胰系MRI,据此进行定位、定性诊断,并与B超,CT,ERCP及手术和病理结果相比较。结果:口服枸橼酸铁铵后MRCP图像质量明显提高,对低位梗阻性黄疸的定位定性诊断准确率达97.22%,优于B超(P<0.05),与CT,ERCP无显著差异。结论:口服枸橼酸铁铵后MRCP结合常规MRI在低位梗阻性黄疸的定位、定性诊断上具有很高的准确性,是一种安全、简便、无创伤的诊断方法。

Objective To evaluate the value of oral ferric ammonium citrate solution as a gastrointestinal contrast agent in diagnosing low-level obstructive jaundice. Methods Thirty-six patients who were suspected of low-level obstructive jaundice were performed with magnetic resonance cholangiopancreatography （MRCP） and conventional MRI before and after the administration of oral ferric ammonium citrate solution. The diagnostic accuracy for evaluating the site and the cause of obstruction was compared with other diagnostic modalities. Results The image qualities of single-slice and multi-slice MRCP were improved markedly. The accuracy of MRCP for evaluating the site of obstruction was 97.22% , which was superior to US （P 〈 0.05 ）. There were no significant differences among the MRCP, CT, and ERCP. Conclusion Oral ferric ammonium citrate solution can significandy improve the image quality of MRCP. FAC-MRCP is a simple, safe, and noninvasive technique with excellent accuracy in the diagnosis of low-level obstructive jaundice.