^(18)FDG-PET/CT及CeMSCT联合诊断原发性肝细胞癌研究

Application of ^(18)FDG-PET/CT and CeMSCT in primary hepatocellular carcinoma

目的探讨联合应用PET/CT及MSCT在肝脏原发性肝细胞癌中的诊断价值。方法收集明确诊断的原发性肝癌38例,18FDG-PET及CeMSCT检查后进行回顾性总结分析,按病灶大小进行分组,并按浓聚程度不同进行分级(1-4级)。结果CeM-SCT对肝癌诊断敏感性为68.4%,PET/CT对肝癌诊断敏感性为52.6%,联合诊断肝癌的敏感性为73.7%。病灶大小之间诊断效能有差异,肝癌的浓聚程度分级1-2级占55.3%,3-4级占44.7%。结论联合应用PET/CT及CeMSCT对原发性肝细胞癌可以提高大于3 cm肝癌诊断的敏感性,并对临床分期、指导治疗和预后的判断具有重要的价值,对于小于3 cm肝癌联合诊断仍需进一步探讨。

Objective To investigate the diagnostic value of PET/CT and CeCT in primary hepatocellular carcinoma. Methods thirty-eight cases with primary hepatoeellular carcinoma which had been clearly diagnosed by pathology, have been examined by PET/CT and CeMSCT, and then we analyzed retrospectively these data by PET and CT specialists. We divide two groups according to the size of focal and classified four grade according to different dense degree. Results The sensitivity of CeMSCT is 68.4% in primary hepatoeellular carcinoma diagnosis and PET/CT was 52.6% and PET plus CeMSCT was 73.7%. There are significance different in two groups in the diagnosis power. According to different grade eriterionl, 1 -2grade was 55.3% and 3 -4 grade was 44.7%. Conclusion Combined PET/CT and CeMSCT may improve the sensitivity in primary hepatoeellular carcinoma of 〉 3cm, and at same time, it is very important for patients to renew elinieal stage and direet treatment and predietion prognostie, but there are no important value in less 3cm focal of primary hepatoeellular carcinoma.