盐酸倍他洛尔片含量的紫外分光光度法测定

Determination of Betaxolol hydrochloride by ultraviolet spectrophotometry

目的：建立盐酸倍他洛尔片剂含量的紫外分光光度测定法。方法：采用紫外分光光度法,以水为空白对照,273nm为测定波长,测定盐酸倍他洛尔的含量。结果：盐酸倍他洛尔质量浓度在50.02-300.04mg/L范围内线性关系良好（r=0.9999,n=5）,平均加样回收率为99.36%。结论：该法操作简便、精密度好、结果可靠,适用于盐酸倍他洛尔片含量的快速测定。

Aim： To establish ultraviolet spectrophotometry method for the determination of Bctaxolol hydroehloride. Methods：The contents of Betaxolol hydrochloride were determined at 273 nm with water as the blank control by ultraviolet spectrophotometry. Results： The calibration curve of Betaxolol hydrochloride was linear when its concentration range was from 50.02 to 300.04 mg/L（r = 0. 999 9, n = 5）, and the average recovery was 99.36%. Conclusion： The method is convenient in operation, precise, reliable in results, and can be used as rapid determination for Betaxolol hydrochloride in tablets.