人乳腺浸润性导管癌薄层断面解剖及三维重建

Thin sectional anatomy and three dimensional reconstruction of breast invasive ductal carcionma

目的研究数字化虚拟人乳腺浸润性导管癌三维重建方法,探讨肿瘤空间生长特征。方法对术前穿刺明确诊断的浸润性导管癌手术切除全乳标本进行薄层铣切,取得全乳连续图像,采用3DDOCTOR软件生成三维立体图,观察肿瘤薄层断面及三维特征。结果乳腺薄层断面各结构清晰,乳房实体有较强的立体感,通过上下左右不同层面的旋转,可了解肿瘤各个空间方向的生长方式。结论人乳腺浸润性导管癌铣切图像精确,三维重建图像清晰,可较准确反映乳腺癌在乳房中结构特征及生长方式,对乳腺癌保乳手术切除范围判定有指导意义。

Objective To study the methods of three dimensional reconstruction of digitized virtual breast invasive ductal carcionma and sterical characteristic of tumor growth. Methods The specimens were sliced into 0.2 mm continuous sections on transversal plane with the computerized miller, and photographs were taken with digital camera. 3DDOCTOR software was used to make three dimensional block diagram and the thin sectional and three dimentional characteristics of breast invasive ductal carcionma were observed. Results Every structure of breast in thin section was clear. Stereo image of breast solid could be shown satisfactorily. Every shape of stereo image and the structure of breast could be shown by revolving the three dimensional image in different direction, beneficial to us in understanding the dimensional growth pattern of tumor. Conclusion The sliced image of breast invasive ductal carcionma database was exact. The image of three dimentional reconstruction was clear, which could reflect the structural feature and growth pattern of breast carcinoma in the breast exactly and be conducive to the evaluation of tumor margin in breast conservation therapy.