2Barille S,Akhoundi C,Collette M,et al.Metalloproteinases in multiple myeloma:production of Matrix Metalloproteinases-9(MMP-9),activation of proMMP-2,and induction of MMP-1 in myeloma cell[J].Blood,1997,90(4):1649-1655.
3Uneda S,Hata H,Matsuno F,et al.Macrophage inflammatory protein 1-alpha is produced by human multiple myeloma (MM) cells and its expression correlates with bone lesions in patients with MM[J].Br J haematol,2003,120(1):53-55.
4Oyajobi BO,Franchin G,Williams PJ,et al.Dual effects of macrophage inflammatory protein-1 alpha on osteolysis and tumor burden in the 5TGM1 model of myeloma bone disease[J].Blood,2003,102(1):311-319.
二级参考文献8
1Bellamy WT. Expression of vascular endothelial growth factor and its receptors in multiple myeloma and other hematopoietic malignancies.Semin Oneol, 2001, 28: 551-559.
2Dankbar B, Padre T, Leo R, et al. Vascular endothelial growth factor and interleukin-6 in paracrine tumor-stromal cell in teractions inmultiple myeloma. Blood, 2000, 95 : 2630-2636.
4Gupta D, Treon SP, Shima Y, et al. Adherence of multiple myeloma cells to bone marrow stromal ceils upregulates vascular endothelial growth factor secretion: therapeutic applications. Leukemia, 2001,15 : 1950-1961.
5Bisping G, Leo R, Wenning D, et al. Paracrine interactions of basic fibroblast growth factor and interleukin-6 in multiple myeloma.Blood, 2003, 101: 2775-2783.
6Hideshima T, Akiyama M, Hayashi T, et al. Targeting p38 MAPK inhibits multiple myloma cell growth in the bone marrow milieu.Blood, 2003, 101 : 703-705.
7Hideshima T, Chauhan D, Schlossman R, et al. The role of tumor necrosis factor a in the pathophysiology of human multiple myeloma:therapeutic applications. Oncogene, 2001,20: 4519-4527.
8Lin B, Podar K, Gupta D, et al. The vascular endothelial growth factor receptor tyrosine kinase inhibior PTK787/ZK222584 inhibits growth and migration of multiple myeloma cells in the bone marrow microenvironment. Cancer Res, 2002, 62 : 5019-5026.