期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

患者体重对体外受精-胚胎移植结局的影响 被引量：3

Effects of body weight on the outcome of the patients receiving in vitro fertilization and embryo transfer(IVF-ET) treatment
下载PDF
导出
摘要 目的:探讨患者体重对体外受精-胚胎移植(IVF-ET)结局的影响。方法:选择140例首次接受IVF-ET助孕的患者为研究对象,按体重指数(BMI)分成超重组37例(BMI≥24 kg/m2)及正常体重组103例(BMI<24 kg/m2),回顾性分析比较两组患者促性腺激素(Gn)用量及使用时间、取卵数、受精率、妊娠率、卵巢过度刺激综合征(OHSS)发生率及未移植率。结果:超重组Gn的使用时间(11.43±2.01)天、OHSS发生率(13.51%)及未移植率(10.81%)明显高于正常体重组〔分别为(9.79±1.46)天、2.51%及0.97%〕,两者比较,差异有统计学意义(P<0.05);其余各指标两组比较,差异无统计学意义(P>0.05)。结论:超重对IVF-ET妊娠结局有一定的负面影响,因此在接受IVF-ET治疗前指导患者适当减轻体重可能会改善IVF-ET结局。 Objective： The aim of this study was to evaluate the effects of body weight on the outcome of patients receiving in vitro fertilization and embryo transfer （IVF- ET） treatment. Methods： A retrospective study was carried out on 140 patients who first received IVF - ET. According to their body mass index （ BMI）, they were divided into two groups by a cutoff of 24 kg/m^2 ： normal weight （ BMI 〈 24 kg/m^2, P = 103 ） and overweight （ BMI 〉124 kg/m2, n = 37）, and these two groups were compared in regards to the outcome of IVF - ET. Results： Days of stimulation and hyperstimulation in the overweight group was higher than the normal weight group （ P 〈 0. 05 ） ; There were no significant differences in other indexes between the two groups. Conclusion： Overwei - ght can take some negative effects on the outcome of IVF- ET, so loss weight to overweight patients before IVF- ET may improve the outcome.
作者 程昭霞 谭季春 曲文玉 回艳涛
机构地区 辽宁省沈阳市妇婴医院生殖中心
出处 《中国妇幼保健》 CAS 北大核心 2007年第15期2101-2103,共3页 Maternal and Child Health Care of China
关键词 体重指数 体外受精-胚胎移植 Body mass index Fertilization In vitro Embryo Transfer
分类号 R321.33 [医药卫生—人体解剖和组织胚胎学] R711.6 [医药卫生—妇产科学]
  • 相关文献

参考文献11

  • 1Dechaud H,Anahory T,Reyftmann L et al.Obesity does not adversely affect results in patients who are undergoing in vitro fertilization and embryo transfer.Eur J Obstet Gynecol Reprod Biol,2006,127:88 ～93
  • 2Seung YK,Sang DK,Byung CJ et al.Clinical efficacy of body mass index as predictor of in vitro fertilization and transfer outcomes.J Korean Med Sci,2006,21:300 ～303
  • 3Loveland JB,McClamrock HD,Malinow AM et al.Increased body mass index has a deleterious effect on in vitro fertilization outcome.J Assist Reprod Genet,2001,18:382 ～386
  • 4Frattarelli JL,Kodama CL.Impact of body mass index on in vitro fertilization outcomes.J Assist Reprod Genet,2004,21:211 ～5
  • 5Pasquali R,Pelusi C,Genghini S et al.Obesity and reproductive disorder in women.Hum Reprod Update,2003,9:359 ～ 372
  • 6Steinkampf MP,Hammond KR,Nichols JE et al.Effect of obesity on recombinant follicle stimulating hormone absorption:subcutaneous versus intramuscular administration.Fertil Steril,2003,80:99 ～ 102
  • 7Urman B,Fluker MR,Yuen BH et al.The outcome of in vitro fertilization and embryo tran-sfer in women with polycystic ovary syndrome failing to conveive after ovulation induction with exogenous gonadtropins.Fertile Steril,1992,57:1269 ～ 1273
  • 8Anjua D,Lindsey B,Jill B et al.Obstetric outcomes after in vitro fertilization in obese and morbidly obese women.Obstet Gynecol,2006,108:61～69
  • 9Styne-Gross A,Elkind-Hirsch K,Scott RT.Obesity does not impact implantation rates or pre-gnancy outcome in women attempting conception through oocyte donation.Fertil Steril,2005,83:1629 ～1634
  • 10Anifandis G,Koutselini E,Stefanidis I et al.Serum and follicular fluid leptin levels are correlated with human embryo quality.Reproduction,2005,130:917 ～921

同被引文献13

  • 1Rich-Edwards JW,Spiegelman D,Garland M,et al.Physical activity,body mass index,and ovulatory disorder infertility[J].Epidemiology,2002,13(2):184-190.
  • 2Fedorcsák P,Dale PO,Storeng R,et al.Impact of overweight and underweight on assisted reproduction treatment[J].Hum Reprod,2004,19(11):2523-2528.
  • 3Pasquali R,Pelusi C,Genghini S,et al.Obesity and reproductive disorders in women[J].Hum Reprod Update,2003,9(4):359-372.
  • 4Zachariah M,Fleming R,Acharya U.Management of obese women in assisted conception units:a UK survey[J].Hum Fertil,2006,9(2):101-105.
  • 5Matalliotakis I,Cakmak H,Sakkas D,et al.Impact of body mass index on IVF and ICSI outcome:a retrospective study [J].Reprod Biomed,2008,16(6):778-783.
  • 6Hillier SG.The Parkes lecture:controlled ovarian stimulation in women[J].J Reprod Fertil,2000,120(2):201-210.
  • 7Rich - Edward JW, Spiegelman D, Garland M, et al. Physical activity, body mass index, and ovulatory disorder infertility [ J ]. Epidemiology, 2002,13 (2) : 184 - 190.
  • 8Zaidi S,Usmani A,Shokh IS,et al. Ovarian rerve and BMI between fertile and subfertile women [ J ]. J Coil Physician Surg Pak, 2009,19 (1):21 -24.
  • 9Fedorcsak P, Dale PO, Storeeng R, et al. Impact of overweight and un- derweight on assisted reproduction treatment [ J ]. Hum Reprod,2004, 19( 11 ) : 2523 -2528.
  • 10Thum MY, E1 -Sheikhah A, Faris R, Parikh J, Wren M, Ogunyemi T, Gafar A, Abdalla H. The influence of body mass index to in - vitro fertilisation treatment outcome, risk of miscarriage and pregnan- cy outcome. [ J] Hum Fertil (Camb) ,2001,4 ( 1 ) : 37 -42.

引证文献3

二级引证文献19

中国妇幼保健
2007年 第15期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部